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Qom Univ Med Sci J 2019, 13(8): 26-32 Back to browse issues page
Comparison of Serum Levels of Vitamin D in Nulliparous Women with Severe Preeclampsia with Healthy Pregnant Woman
Shima Mohammadian1 , Narges Mohammadsalehi * 2, Yousef Mohammadian3
1- Department of Obstetrics & Gynecology, Faculty of Medicine, Qom University of Medical Sciences, Qom University of Medical Sciences
2- Department of Epidemiology, Neuroscience Research Center, Qom University of Medical Sciences , nm.salehy@gmail.com
3- Student Research Committee, Faculty of Medicine, Shahroud University of Medical Sciences, School of Medicine, Shahrud University of Medical Sciences
Abstract:   (309 Views)
Background and Objectives: Hypertensive disorders are one of the causes of morbidity and mortality, which occur in 5% of pregnancies. One of the causes of preeclampsia, is inappropriate regulation of activator of placental Cyp27B1 enzyme, which is induced by vitamin D deficiency. This study aimed to assess the relationship between the level of vitamin D with risk of preeclampsia in pregnant women.
Methods: This case-control study, was performed on 140 pregnant women referred to Alzahra hospital of the Qom University, 70 patients with severe preeclampsia were included in the case group and 70 healthy pregnant women in terms of preeclampsia, were assigned to the control group. Blood samples were assessed in terms of vitamin D using immunoassay method from 2016 to 2017. Data analysis was performed by t test and Chi square test.
Results: In this study, according to the results of t test, the mean serum level of vitamin D in preeclampsia group was 13.77±8.53ng/ml and in the control group, was 16.73±6.82ng/ml, which was statistically significant (p<0.05).
Conclusion: In the present study, the results showed that mothers with preeclampsia are at risk of vitamin D deficiency, Therefore, adequate administration of vitamin D can be effective in the prevention of preeclampsia.
Keywords: Vitamin D, Pre-eclampsia, Pregnancy
Full-Text [PDF 1015 kb]   (84 Downloads)    
Type of Study: Original Article | Subject: زنان
Received: 2019/02/17 | Accepted: 2019/08/25
* Corresponding Author Address: Deputy Of Rrsearch & Technology
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Mohammadian S, Mohammadsalehi N, Mohammadian Y. Comparison of Serum Levels of Vitamin D in Nulliparous Women with Severe Preeclampsia with Healthy Pregnant Woman. Qom Univ Med Sci J. 2019; 13 (8) :26-32
URL: http://journal.muq.ac.ir/article-1-2413-en.html

Volume 13, Issue 8 (October 2019) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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