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:: Volume 10, Issue 11 (January 2017) ::
Qom Univ Med Sci J 2017, 10(11): 9-16 Back to browse issues page
The Effect of 4 Weeks of Flaxseed Extract Supplementation on Serum Concentration of Brain-Derived Neurotrophic Factor and C-Reactive Protein
Hosein Nazari *1, Eisa Tahmasbpoor 2, Zia Fallah Mohammadi 3, Ghsem Mohammadpoor 4, Shamseddin Rahimizadeh 5
1- Msc University of Mazandaran , knazari66@yahoo.com
2- Phd Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
3- Phd University of Mazandaran
4- Phd Islamic Azad University
5- Msc Shiraz University
Abstract:   (565 Views)

Background and Objective: Omega-3 Supplementation has different effects on the body. Terefore, this study was carried out with the aim of investigating the effect of 4 weeks of flaxseed extract supplementation on serum concentrations of Brain-derived neurotrophic factor (BDNF) and C-reactive protein (CRP).

Methods: In this double-blind study, 24 male students (mean age, 23.21±1.98) were randomly divided into two groups, including flaxseed extract (n=12) and placebo (n=12). After 4 weeks of supplementation with flaxseed extract, serum levels of BDNF and CRP was measured in fasting state. BDNF level was measured using an enzyme-linked immunosorbent assay (ELISA) kit, and CRP level was measured using an immunoturbidimetric assay kit. Data were analyzed using t-test. The level of significance was set at p<0.05.

Results: After four weeks of supplementation with flaxseed extract the mean serum level of BDNF significantly increased (p<0.001), but no significant change was observed in the serum level of CRP (p<0.591).

Conclusion: It seems that supplementation with flaxseed extract through increasing BDNF level is useful for the improvement of cognitive and functional benefits of the brain.

Keywords: Brain-derived neurotrophic factor, C-reactive protein, Flax, Omega-3
Full-Text [PDF 391 kb]   (411 Downloads)    
Type of Study: Original Article | Subject: تغذیه
Received: 2016/02/21 | Accepted: 2016/02/25 | Published: 2017/01/24
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Nazari H, Tahmasbpoor E, Fallah Mohammadi Z, Mohammadpoor G, Rahimizadeh S. The Effect of 4 Weeks of Flaxseed Extract Supplementation on Serum Concentration of Brain-Derived Neurotrophic Factor and C-Reactive Protein . Qom Univ Med Sci J . 2017; 10 (11) :9-16
URL: http://journal.muq.ac.ir/article-1-295-en.html
Volume 10, Issue 11 (January 2017) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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