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:: Volume 10, Issue 1 (March 2016 2016) ::
Qom Univ Med Sci J 2016, 10(1): 88-93 Back to browse issues page
A Report of a patient with Diarrhea: Pseudomembranous Colitis
Ahmad Hormati 1, Mohammad Reza Ghadir 1, Seyed Saeed Sarkeshikian 1, Mahdi Mahdi Pezeshki Modarres 2, Faezeh Alemi * 3, Mahdieh Ghoddoosi 2
1- 1Gastroenterology & Hepatology Research Center, Qom University of Medical Sciences, Qom, Iran.
2- 2Qom University of Medical Sciences, Qom, Iran.
3- 3Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran. , faezeh.alemi@gmail.com
Abstract:   (2512 Views)

Background and Objectives: Pseudomembranous colitis is an advanced form of infection with clostridium difficile, which damage epithelial cells following colonization in the intestine and production of toxins A and B. Diarrhea is the most common clinical manifestation caused by C. difficile, which in these cases, blood is never observed macroscopically in the stool. Antibiotic exposure is the main risk factor for this infection and is especially associated with ampicillin, clindamycine, and 2nd and 3rd generation cephalosporins, such as ceftriaxone, cefotaxime, and ceftazidime. To confirm the diagnosis of infection, assessment of the microorganism toxins in the stool by PCR as well as observation of pseudomembrane in colonoscopy, was performed. In this article, a case of an old patient with diarrhea (pseudomembranous colitis) was presented in this article.

Case Report: The patient is an 85-year-old man with signs of weakness, fatigue, fever and chills, and non-productive cough and diagnosis of pneumonia underwent antibiotic therapy, and in the course of treatment, he demonstrated massive watery diarrhea. Laboratory colonoscopy findings was indicative of infection with C. difficile.

Keywords: Clostridium difficile, Enterocolitis, Pseudomembranous, Diarrhea
Full-Text [PDF 333 kb]   (2003 Downloads)    
Type of Study: Case Report Article |
Received: 2016/03/14 | Accepted: 2016/03/14 | Published: 2016/03/14
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Hormati A, Ghadir M R, Sarkeshikian S S, Mahdi Pezeshki Modarres M, Alemi F, Ghoddoosi M. A Report of a patient with Diarrhea: Pseudomembranous Colitis. Qom Univ Med Sci J . 2016; 10 (1) :88-93
URL: http://journal.muq.ac.ir/article-1-442-en.html


Volume 10, Issue 1 (March 2016 2016) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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