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:: Volume 6, Issue 4 (12-2012) ::
Qom Univ Med Sci J 2012, 6(4): 117-125 Back to browse issues page
A Case Report of Successful Treatment of HELLP Syndrome and Thrombotic Thrombocytopenic Purpura by Plasmapheresis
J Vafaeemanesh * 1, M Parham 2
1- Qom University of Medical Sciences , j.vafaeemanesh@muq.ac.ir
2- Qom University of Medical Sciences
Abstract:   (1291 Views)

Background and Objectives: HELLP syndrome was described in 1982 by Weinstein as a triad of hemolysis, elevated liver enzymes and thrombocytopenia. This syndrome develops antepartum in 70% and postpartum in 30% of cases. HELLP syndrome occurs in 0.5 to 0.9% of all pregnancies and is accompanied by disseminated intravascular coagulation (DIC) in 38% of patients. Maternal mortality rate is reported to be 1.1%. Although thrombotic thrombocytopenic purpura (TTP) is rare, it is one of the most important differential diagnoses for HELLP syndrome, which may be lethal without appropriate treatment. Plasmapheresis is one of the recommended treatments in complicated and/or resistant to treatment cases.

Case Report: In this article we introduce a 22 years old primiparous woman with a term pregnancy that developed HELLP syndrome and DIC after delivery. Due to the lack of improvement, an accompany of TTP was diagnosed. So, she underwent plasmapheresis treatment and was discharged with full recovery after 22 sessions of treatments.

Keywords: Help Syndrome, Purpura, Thrombic Thrombocytopenic, Plasmapheresis, Disseminated Intravascular Coagulation
Full-Text [PDF 1041 kb]   (2208 Downloads)    
Type of Study: Case Report Article |
Received: 2016/04/5 | Accepted: 2016/04/5 | Published: 2016/04/5
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Vafaeemanesh J, Parham M. A Case Report of Successful Treatment of HELLP Syndrome and Thrombotic Thrombocytopenic Purpura by Plasmapheresis . Qom Univ Med Sci J . 2012; 6 (4) :117-125
URL: http://journal.muq.ac.ir/article-1-542-en.html


Volume 6, Issue 4 (12-2012) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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