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:: Volume 10, Number 8 (October 2016) ::
Qom Univ Med Sci J 2016, 10(8): 18-26 Back to browse issues page
The Effect of Flaxseed Oil on Memory Process in Adult Male Wistar Rats
Fatemeh Khademisar1, Akram Eidi *2, Shahrbanoo Oryan3
1- MSc Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
2- Full Prof. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran , akram_eidi@yahoo.com
3- Full Prof. Biological Science Faculty, Kharazmi University, Tehran, Iran
Abstract:   (734 Views)

Abstract

Background and Objectives: Flaxseed has been considered as an important functional food due to its high content of α-linolenic acid, lignans, and fiber. Flaxseed has health benefits, such as in reduction of cardiovascular disease, atherosclerosis, diabetes, cancer, arthritis, osteoporosis, neurological disorders, and autoimmunity. In the present study, the effects of flaxseed oil on memory retention, was investigated in adult male rats using passive avoidance learning task.

Methods: In this experimental study, 30 male Wistar rats were randomly divided into 5 groups. The animals of control group were intact. The experimental rats intraperitonealy received flaxseed oil at doses of 0.5, 1.0, 1.5, and 2ml/kg body weight. Twenty-four hours after training, memory retention was evaluated using passive avoidance learning task. The step-through latency and time in dark compartment was measured. The data were analyzed using one-way ANOVA and Dunett statistical tests. The level of significance was considered p<0.05.

Results: Post-training treatment with flaxseed oil (at doses of 1.5 and 2ml/kg body weight) significantly increased the step-through latency time and significantly decreased the time in the dark compartment compared to the control group (p<0.05).

Conclusion: The results of this study showed that flaxseed oil significantly improves the retention memory process.

Keywords: Linseed oil; Memory; Rats.

Keywords: Linseed oil, Memory, Rats.
Full-Text [PDF 576 kb]   (468 Downloads)    
Type of Study: Original Article | Subject: فیزیولوژی
Received: 2016/04/10 | Accepted: 2016/04/11 | Published: 2016/10/27
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Khademisar F, Eidi A, Oryan S. The Effect of Flaxseed Oil on Memory Process in Adult Male Wistar Rats. Qom Univ Med Sci J . 2016; 10 (8) :18-26
URL: http://journal.muq.ac.ir/article-1-669-en.html
Volume 10, Number 8 (October 2016) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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