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:: Volume 10, Issue 10 (December 2017) ::
Qom Univ Med Sci J 2017, 10(10): 50-60 Back to browse issues page
Evaluation of Risk Factors for Acute Coronary Syndrome in Patients Referring to the Cardiology Clinic of Shahid Beheshti Hospital in Qom City, 2015, Iran
Jamshid Vafaeimanesh 1, Fakhrodin Hejazi 1, Mostafa Vahedian 1, Reihane Tabaraii 1, Mohammad Bagherzadeh *2, Ali Akbar Khalesi 3
1- Qom University of Medical Sciences
2- Qom University of Medical Sciences , m_bagherzadeh3@yahoo.com
3- Iran University of Medical Sciences
Abstract:   (726 Views)

Background and Objectives: Cardiovascular diseases are one of the most common causes of fatal diseases in the world. Alterations in biochemical composition of blood plasma are associated with coronary heart disease. In this study, some biochemical markers were investigated in patients suspicious to coronary artery disease (CAD) without acute coronary syndrome symptoms.

Methods: In this descriptive cross-sectional study, 120 patients suspicious to CAD, were ivestigated. In all of them, physical examinations were performed and biochemical parameters, were measured. The patients were divided into CAD-positive and -negative groups, and their biochemical markers were compared.

Results: CAD-positive cases, was significantly associated with Troponin, ESR, and Helicobacter pylori-Positive serology. A significant association was found between age, male gender, BMI, and positive CAD. ESR sensitivity, specificity, positive and negative predictive values and positive and negative likelihood ratio for diagnosis of CAD, were 56.5%, 65.5%, 63.6%, 58.5%, 1.61, and 0.66, respectively. Also, Troponin sensitivity, specificity, positive and negative predictive values, and positive and negative LR, were 18%, 96.5%, 84.5%, 52.3%, 5.2, and 0.85, respectively. A positive correlation was found between Helicobacter pylori-positive serology and CAD-positive cases (1.48-10, CI=95%, OR=3.86, p=0.006).

Conclusion: Based on the findings of the present research, in patients without acute coronary syndrome symptom, only ESR>10mm/h, positive cTnI, and Helicobacter pylori-positive serology had different results between the patients with and without CAD, which can be suggestive of CAD in asymptomatic cases.

Keywords: Coronary artery disease, Biomarkers, Asymptomatic disease
Full-Text [PDF 692 kb]   (555 Downloads)    
Type of Study: Original Article | Subject: بیماریهای قلب
Received: 2016/04/15 | Accepted: 2016/08/17 | Published: 2016/12/25
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Vafaeimanesh J, Hejazi F, Vahedian M, Tabaraii R, Bagherzadeh M, Khalesi A A. Evaluation of Risk Factors for Acute Coronary Syndrome in Patients Referring to the Cardiology Clinic of Shahid Beheshti Hospital in Qom City, 2015, Iran. Qom Univ Med Sci J . 2017; 10 (10) :50-60
URL: http://journal.muq.ac.ir/article-1-719-en.html
Volume 10, Issue 10 (December 2017) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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