[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 10, Issue 2 (April 2016) ::
Qom Univ Med Sci J 2016, 10(2): 23-30 Back to browse issues page
Biosynthesis of Gold Nanoparticles Using Persian Clover Seed Extracts
Mehrdad Khatami * 1, Meysam Soltaninejad 2, Keyghobad Kaikavoosi 3
1- Bam University of Medical Sciences , mehrdad7khatami@gmail.com
2- Bahonar University of Medical Sciences
3- azad University
Abstract:   (3150 Views)

Abstract

Background and Objectives: Synthesis of gold nanoparticles is very valuable due to its numerous applications in detection of pathogens, cancer therapy and targeted drug delivery. In this study, the synthesis of gold nanoparticles using Persian clover seed extract as a natural source of both reducing and stabilizing agents, was investigated.

Methods: Change of the color of clover seed extract immediately after treatment with hydrogen gold tetrachloride showed the first visible sign of the synthesis of gold nanoparticles. The synthesized nanoparticles were characterizeed using UV visible spectrophotometry, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and transmission electron imaging (TEM).

Results: The broad and strong peak of UV visible spectrophotometry at a wavelength of 534 nm indicated the formation of gold nanoparticles. X-ray diffraction pattern confirmed the formation of crystalline structure of gold nanoparticles. The results of Fourier transform infrared spectroscopy showed the involvement of aromatic, amine, and carboxyl groups exist in Persian clover seed extract in the synthesis of gold nanoparticles. Transmission electron image identified the formation of spherical nanoparticles with a size range of 1-30nm and with the most frequency in size of 20-25nm. Synthesized gold nanoparticles remained stable in vitro for up to 2 months with no sediment production or reduction in the frequency of gold nanoparticles.

Conclusion: With respect to the results of this study, biosynthesis of gold nanoparticles was very low-cost and without need of energy. The synthesized gold nanoparticles can be used in researches on detection of pathogens, cancer therapy, and targeted drug delivery.

Keywords: Biosynthesis, Metabolism, Gold nanoparticles, X-ray diffraction.
Full-Text [PDF 612 kb]   (3102 Downloads)    
Type of Study: Original Article |
Received: 2016/04/17 | Accepted: 2016/04/17 | Published: 2016/04/17
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Khatami M, Soltaninejad M, Kaikavoosi K. Biosynthesis of Gold Nanoparticles Using Persian Clover Seed Extracts. Qom Univ Med Sci J . 2016; 10 (2) :23-30
URL: http://journal.muq.ac.ir/article-1-730-en.html


Volume 10, Issue 2 (April 2016) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
Persian site map - English site map - Created in 0.19 seconds with 30 queries by YEKTAWEB 3781