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:: Volume 11, Number 2 ( April 2017 2017) ::
Qom Univ Med Sci J 2017, 11(2): 38-45 Back to browse issues page
The Effect of 12-Week Resistance Training on Cardiac Hypertrophy, Glucose Level, Insulin, and Insulin Resistance Index in STZ-Induced Diabetic Rats
Rasoul Mohammadi1, Hasan Matin Homaee *2, Mohammad Ali azarbayjani3, Kazem Baesi4
1- PhD student Islamic Azad University, Central Tehran Branch
2- Assistant Professor Islamic Azad University, Central Tehran Branch , Hasanmatinhomaee@yahoo.com
3- Professor Islamic Azad University, Central Tehran Branch
4- Assistant Professor Pasteur Institute of Iran
Abstract:   (543 Views)

Background and Objectives: Type 2 diabetes is a risk factor for heart disease and has a major contribution in mortality due to cardiovascular diseases. In the present study, the effect of 12-week resistance training was investigated on cardiac hypertrophy, glucose, level, insulin, and insulin resistance index in STZ-induced diabetic rats.

Methods: A total of 16 male Wistar rats (mean weight, 200±20g) were randomly divided into two groups of diabetic control and (N= 8), diabetic resistance (N= 8). The diabetic resistance training group performed a 12-week resistance training, and 48 hours after the end of the last training session, the rats were anesthetized and euthanized. The variables of interest (body weight, heart weight, left ventricular weight, percentage of heart weight to body weight, percentage of left ventricular weight to heart weight, resting heart rate, level of glucose, insulin, and insulin resistance index), were measured. Data analysis was performed using independent samples t-test at significance level of p≤0.05.

Results: There was a significant difference among mean heart weight (p=0.050), left ventricular weight (p=0.002), level of glucose (p=0/000), insulin (p=0.000), and resting heart rate (p=0.021) in the resistance diabetic group compared to the control diabetic group.

Conclusion: According to the results of the present study, it seems that resistance training is an important strategy to improve the structure and function of the heart in diabetics and it can be considered as an effective intervention method.

Keywords: Resistance training, Diabetes mellitus, Rats
Full-Text [PDF 422 kb]   (571 Downloads)    
Type of Study: Original Article | Subject: فیزیولوژی ورزشی
Received: 2016/03/12 | Accepted: 2016/04/25 | Published: 2017/04/22
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Mohammadi R, Matin Homaee H, azarbayjani M A, Baesi K. The Effect of 12-Week Resistance Training on Cardiac Hypertrophy, Glucose Level, Insulin, and Insulin Resistance Index in STZ-Induced Diabetic Rats. Qom Univ Med Sci J . 2017; 11 (2) :38-45
URL: http://journal.muq.ac.ir/article-1-436-en.html
Volume 11, Number 2 ( April 2017 2017) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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