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:: Volume 10, Issue 10 (December 2017) ::
Qom Univ Med Sci J 2017, 10(10): 86-99 Back to browse issues page
DNA Vaccine: The Third Generation Vaccine
Roghayeh Teimourpour 1, Zahra Meshkat *2, Mohsen Arzanlou 1, Hadi Peeridogaheh 1
1- Ardabil University of Medical Sciences
2- Professor Mashhad University of Medical Sciences , meshkatz@mums.ac.irourr881@mums.ac.ir
Abstract:   (871 Views)

Background and Objectives: After live attenuated and subunit vaccines, DNA vaccines were introduced as a third generation vaccine in the field of vaccinology. This type of vaccine is a promising approach to deal with infectious agents in the future. Although, many aspects of this type of vaccine has not yet been identified, its use has been initiated in humans and clinical trials, and several DNA vaccines have been developed against veterinary infectious diseases. This generation of vaccine has provided new approaches to deal with and control existing diseases. In addition to infectious diseases, this type of vaccine can also be used against different types of tumors. Despite numerous attempts, only one type of DNA vaccine has been approved for use in human. The present study focuses on biology, advantages, and disadvantages of DNA vaccine and investigates its capacity in stimulating different types of immune responses.

Keywords: DNA, Vaccines, Subunit, Clinical trial
Full-Text [PDF 862 kb]   (1991 Downloads)    
Type of Study: Review Article | Subject: میکروب شناسی
Received: 2016/05/1 | Accepted: 2016/05/1 | Published: 2016/12/26
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Teimourpour R, Meshkat Z, Arzanlou M, Peeridogaheh H. DNA Vaccine: The Third Generation Vaccine. Qom Univ Med Sci J . 2017; 10 (10) :86-99
URL: http://journal.muq.ac.ir/article-1-792-en.html
Volume 10, Issue 10 (December 2017) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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