Qom University of Medical Sciences Journal

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Background and Objectives: The fibrinolytic system is an important physiological mechanism, the function of which is decomposition of fibrin strands in blood vessels. In the present study, the effect of one season of preparation and competition, was investigated on fibrinolysis, D-dimer, and CRP indices in professional soccer players.
 
Methods: In this semi-experimental study, 10 soccer players of Sanat Naft Abadan (age, 22.5±2.7 years; weight, 71±4kg; height, 178.5±4.5cm; BMI, 22.2±0.4kg/m²), participated in this study. The subjects performed one season of soccer preparation and competition, which lasted about 10 months. Blood samples (for measuring t-PA, PAI-1, D-dimer, and CRP), were taken in four stages: before the preparation season, after the preparation season, half-season, and at the end of competition season. Data were analyzed using repeated ANOVA and Bonferroni tests.
 
Results: The training period caused a significant change in t-PA (p=0.003) and PAI-1 (p=0.005) resting levels, but caused no change in D-dimer and CRP resting levels. The paired analysis of the data showed a significant difference between the resting levels of t-PA (p=0.002) and PAI-1 (p=0.004) before the preparation period and after the competition season.
 
Conclusion: According to the findings of this research, training causes an increase in the fibrinolysis system potential, hence, this may cause a decrease in the formation of thrombosis in professional soccer players.
 
 
 

Keywords: Tissue plasminogen activator, Plasminogen activator inhibitor-1, D-dimer, C-reactive protein, Preparation period.

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