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:: Volume 11, Number 2 ( April 2017 2017) ::
Qom Univ Med Sci J 2017, 11(2): 87-93 Back to browse issues page
Unexpected Regression of a Pancreatic Gastrinoma after Arterial Chemoembolization of its Hepatic Metastases: Case Report
Seyed Saeid Sarkeshikian *1, Mohammad Reza Ghadir2, Ahmad Hormati3
1- assistant professor Digestive Diseases Research Center of Qom University of Medical Siences , ss_sarkeshik@hotmail.com
2- Associate Professor Digestive Diseases Research Center of Qom University of Medical Siences
3- assistant professor Digestive Diseases Research Center of Qom University of Medical Siences
Abstract:   (381 Views)

Background and Objectives: Gastrinoma is a rare cause of peptic ulcers and should be suspected when manifestations, ulcer site, and response to treatment are not normal. Gastrinomas are mostly malignant and liver is the most common site of their metastasis. Arterial chemoembolization (obstruction by blood clotting with chemicals) and arteries that feed metastases, is used as a method to reduce the symptoms. Appropriate response is seen in more than half of the patients, although it is short term.

Case report: The patient is a 42-year old man, who was healthy until 4 years ago that experienced acute abdominal pain due to duodenal ulcer rupture and two episodes of acute upper gastrointestinal bleeding due to perforation of two separate duodenal ulcers within 2 months of each other. He also complained of mild diarrhea and loss of appetite at that time. Laboratory examinations showed increased serum level of gastrin. Abdominal CT scan showed a small pancreatic head mass and three hepatic mass with increased contrast medium absorption. In CT-guided biopsy report, pancreatic head mass and uniform and apparently benign cells similar to islet cell tumor, were seen. Chemoembolization of liver metastasis arteries was performed, which after 6 months, CT scan showed almost complete regression of metastases and also primary pancreatic lesion.

Keywords: Gastrinoma, Liver, Neoplasm metastasis, chemoembolization Therapeutic
Full-Text [PDF 1623 kb]   (170 Downloads)    
Type of Study: Case Report Article | Subject: گوارش
Received: 2016/05/8 | Accepted: 2016/10/2 | Published: 2017/04/22
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Sarkeshikian S, Ghadir M R, Hormati A. Unexpected Regression of a Pancreatic Gastrinoma after Arterial Chemoembolization of its Hepatic Metastases: Case Report. Qom Univ Med Sci J . 2017; 11 (2) :87-93
URL: http://journal.muq.ac.ir/article-1-815-en.html
Volume 11, Number 2 ( April 2017 2017) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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