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Soltani Najafabadi F, Amjad L, Shahanipour K, Mashayekh A M. The Effect of Olive Leaf Smoke on the Blood Factors and Tissues in Rats. Qom Univ Med Sci J 2023; 17 : 2819.1
URL: http://journal.muq.ac.ir/article-1-3663-en.html
The Effect of Olive Leaf Smoke on the Blood Factors and Tissues in Rats
Faezeh Soltani Najafabadi1 , Leila Amjad * 2, Kahin Shahanipour1 , Amir Masoud Mashayekh3
1- Department of Biochemistry, Faculty of Basic Sciences, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
2- Department of Biology, Faculty of Basic Sciences, Falavarjan Branch, Islamic Azad University, Isfahan, Iran. , amjad.leila@gmail.com
3- Department of Biology, Faculty of Basic Sciences, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.
Abstract:   (821 Views)
Background and Objectives: This study aims to assess the effect of olive leaf smoke inhalation on the blood Biochemical factors, activity of liver enzymes, and the changes in liver, lung and kidney tissues in male Wistar rats.
Methods: In this experimental study, 21 male Wistar rats were put in three groups of 7, including control, olive smoke for one hour per day, and olive smoke for two hours per day. The levels of glucose, triglyceride, cholesterol, urea, creatinine, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and the activity of liver enzymes including alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate aminotransferase (AST) and gamma-glutamyl transferase (GGT) were measured. Histological changes in liver, kidney, and lung tissues were also investigated. Finally, the data were analyzed statistically by one-way analysis of variance. The significant level was set at P<0.05.
Results: Treatment with olive leaf smoke for two hours significantly increased blood glucose level, but it did not cause significant changes in triglyceride, cholesterol, urea, creatinine, HDL, and LDL levels and ALT enzyme activity (P>0.05). However, it significantly increased the activity of AST and GGT enzymes compared to two other groups (P<0.001). Treatment with olive leaf smoke for one hour did not cause significant changes in these factors.
Conclusion: Treatments with olive leaf smoke for 1 or 2 hours do not cause significant changes in blood biochemical factors. However, the 2-hour treatment can affect the activity of liver enzymes AST, ALP and GGT. The olive leaf smoke has pathological effects on liver, lung and kidney tissues.
Article number: 2819.1
Keywords: Kidney, Liver, Lung, Olea europea, Smoke
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Type of Study: Original Article | Subject: طب سنتی
Received: 2023/01/30 | Accepted: 2023/07/15 | Published: 2023/08/1
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