1- Department of Iranian Medicine, Institute of Medical History Studies, Islamic and Complementary Medicine, Faculty of Iranian Medicine, Iran University of Medical Sciences, Tehran, Iran. 2- Department of Persian Medicine, School of Traditional Medicine, Qom University of Medical Sciences, Qom, Iran. 3- Department of Biostatistics and Epidemiology, School of Health, Environmental Pollution Health Center, Qom University of Medical Sciences, Qom, Iran. 4- Assistant Professor, Department of Health Education and Promotion, School of Health, Qom University of Medical Sciences, Qom, Ira 5- Department of Quranic and Hadith Sciences in Health, Faculty of Health and Religion, Qom University of Medical Sciences, Qom, Iran. 6- Department of Persian Medicine, School of Traditional Medicine, Qom University of Medical Sciences, Qom, Iran. , adanesh@muq.ac.ir
Abstract: (639 Views)
Background and Objectives: Black myrobalan drug, known as “Imam Kazem drug” in Iran, is used by most of Iranian people to prevent and treat the coronavirus disease 2019 (COVID-19). This study aims to investigate the consumption pattern of black myrobalan by people in Qom, Iran and their attitudes towards it. Methods: In this cross-sectional study, 1077 patients referred to health centers in Qom, Iran in 2021 participated. They completed a demographic form and a researcher-made questionnaire assessing the consumption pattern of black myrobalan and people’s attitudes towards this drug. Data were analyzed in SPSS v. 20 software using chi-square test, Fisher test, Spearman correlation test, and logistic regression analysis. Results: Out of 1018 patients who responded to the questionnaire, 660 (64.8%) were familiar with the drug and 491 (48.2%) had used the drug during the COVID-19 pandemic. Among them, 409 (83.2%) had used the drug for prevention and 166 (33.9%) for treatment of COVID-19. The attitude of participants towards this drug was positive in 515 patients (50.6%). The consumption pattern of black myrobalan was significantly correlated with occupation and attitude of people. It was found out that 83 patients (16.9%) reported mild side effects following drug use. Conclusion: A significant percentage of people in Qom city use black myrobalan, and have positive attitude towards it. This requires that its efficacy and side effects be investigated in clinical studies.
Type of Study: Original Article |
Subject: طب سنتی Received: 2022/04/24 | Accepted: 2022/05/15 | Published: 2022/04/30
References
1. Ang L, Song E, Lee HW, Lee MS. Herbal medicine for the treatment of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis of randomized controlled trials. J Clin Med. 2020; 9(5):1583. [PMID] [DOI:10.3390/jcm9051583]
2. Tavakoli A, Vahdat K, Keshavarz M. Novel coronavirus disease 2019 (COVID-19): An emerging infectious disease in the 21st century. Iran South Med J. 2020; 22(6):432-50. [DOI:10.29252/ismj.22.6.432] [DOI:10.29252/ismj.22.6.432]
3. Huang J, Tao G, Liu J, Cai J, Huang Z, Chen JX. Current prevention of COVID-19: Natural products and herbal medicine. Front Pharmacol. 2020; 11:588508. [PMID] [DOI:10.3389/fphar.2020.588508]
4. Panyod S, Ho CT, Sheen LY. Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective. J Tradit Complement Med. 2020; 10(4):420-7. [PMID] [DOI:10.1016/j.jtcme.2020.05.004]
5. Liu M, Gao Y, Yuan Y, Yang K, Shi S, Tian J, et al. Efficacy and safety of herbal medicine (Lianhuaqingwen) for treating COVID-19: A systematic review and meta-analysis. Integr Med Res. 2021; 10(1):100644. [PMID] [DOI:10.1016/j.imr.2020.100644]
6. Luo H, Tang QL, Shang YX, Liang SB, Yang M, Robinson N, Liu JP. Can Chinese medicine be used for prevention of Corona Virus Disease 2019 (COVID-19)? A review of historical classics, research evidence and current prevention programs. Chin J Integr Med. 2020; 26(4):243-50. [PMID] [DOI:10.1007/s11655-020-3192-6]
7. Ang L, Lee HW, Choi JY, Zhang J, Lee MS. Herbal medicine and pattern identification for treating COVID-19: A rapid review of guidelines. Integr Med Res. 2020; 9(2):100407. [PMID] [DOI:10.1016/j.imr.2020.100407]
8. Grigore A, Cord D, Tanase C, Albulescu R. Herbal medicine, a reliable support in COVID therapy. J Immunoassay Immunochem. 2020; 41(6):976-99. [PMID] [DOI:10.1080/15321819.2020.1862867]
9. Tehrani-Banihashemi SA, Asgharifard H, Haghdoost AA, Barghmadi M, Mohammadhosseini N. [The use of complementary/alternative medicine among the general population in Tehran, Iran (Persian)]. Payesh. 2008; 7(4):355-62. [Link]
10. Aghili Khorasani S. Makhzan-ol-Advieh. Tehran: Safirardeha; 2018. [Link]
11. Basha SJ, Jayasankar Reddy , Sudha Rani Y, Koshma M, Hanumanthu G, Dadakhalandar S. A review on Terminalia chebula. Int J Pharmacol Res. 2017; 7(10):187-91. [Link]
12. Deseo MA, Elkins A, Rochfort S, Kitchen B. Antioxidant activity and polyphenol composition of sugarcane molasses extract. Food Chem. 2020; 314:126180. [PMID] [DOI:10.1016/j.foodchem.2020.126180]
13. Miraj S. Pharmacological effects of Saccharum officinarum L. Der Pharm Lett. 2016; 8(13):223-5. [Link]
14. Milia E, Bullitta SM, Mastandrea G, Szotáková B, Schoubben A, Langhansová L, et al. Leaves and Fruits Preparations of Pistacia lentiscus L.: A Review on the Ethnopharmacological Uses and Implications in Inflammation and Infection. Antibiot. 2021; 10(4):425. [PMID] [DOI:10.3390/antibiotics10040425]
15. Paraschos S, Mitakou S, L Skaltsounis A. Chios gum mastic: A review of its biological activities. Curr Med Chem. 2012; 19(14):2292-302. [PMID] [DOI:10.2174/092986712800229014]
16. Özçelik B, Aslan M, Orhan I, Karaoglu T. Antibacterial, antifungal, and antiviral activities of the lipophylic extracts of Pistacia vera. Microbiol Res. 2005; 160(2):159-64. [PMID] [DOI:10.1016/j.micres.2004.11.002]
17. Badgujar SB, Patel VV, Bandivdekar AH. Foeniculum vulgare Mill: A review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology. Biomed Res Int. 2014; 2014:842674. [PMID] [DOI:10.1155/2014/842674]
18. Kesharwani A, Polachira SK, Nair R, Agarwal A, Mishra NN, Gupta SK. Anti-HSV-2 activity of Terminalia chebula Retz extract and its constituents, chebulagic and chebulinic acids. BMC Complement Altern Med. 2017; 17(1):110. [PMID] [DOI:10.1186/s12906-017-1620-8]
19. Li P, Du R, Wang Y, Hou X, Wang L, Zhao X, et al. Identification of chebulinic acid and chebulagic acid as novel influenza viral neuraminidase inhibitors. Front Microbiol. 2020; 11:182. [PMID] [DOI:10.3389/fmicb.2020.00182]
20. Pachi VK, Mikropoulou EV, Gkiouvetidis P, Siafakas K, Argyropoulou A, Angelis A, et al. Traditional uses, phytochemistry and pharmacology of Chios mastic gum (Pistacia lentiscus var. Chia, Anacardiaceae): A review. J Ethnopharmacol. 2020; 254:112485. [PMID] [DOI:10.1016/j.jep.2019.112485]
21. Pazargadi M, Ashktorab T, Alavimajd H, Khosravi S. [Developing an assessment tool for nursing students general clinical performance (Persian)]. Iran J Med Educ. 2013; 12(11):877-87. [Link]
23. Sedighi GH, Maftoon F, Moshrefi M. Knowledge, attitude and use of complementary medicine in Tehran. Payesh. 2004; 3:279-89. [Link]
24. Lotfi MS, Adib-Hajbaghery M, Shahsavarloo ZR, Gandomani HS. The prevalence of traditional and complementary medicine in the general population in Kashan, Iran, 2014. Eur J Integr Med. 2016; 8(5):661-9. [DOI:10.1016/j.eujim.2016.06.006] [DOI:10.1016/j.eujim.2016.06.006]
25. Anbari K, Gholami M. Evaluation of trends in the use of complementary and alternative medicine in health centers in Khorramabad (West of Iran). Glob J Health Sci. 2015; 8(2):72-6. [PMID] [DOI:10.5539/gjhs.v8n2p72]
26. Fesharakinia A, Abedini M. Prevalence of using complementary and alternative medicine in children and its related factors in east Iran. Iran J Pediatr. 2014; 24(1):111-114.
27. Montazeri A, Sajadian A, Ebrahimi M, Haghighat S, Harirchi I. Factors predicting the use of complementary and alternative therapies among cancer patients in Iran. Eur J Cancer Care (Engl). 2007; 16(2):144-9. [PMID] [DOI:10.1111/j.1365-2354.2006.00722.x]
28. Strouss L, Mackley A, Guillen U, Paul DA, Locke R. Complementary and alternative medicine use in women during pregnancy: Do their healthcare providers know? BMC Complement Altern Med. 2014; 14(1):85. [PMID] [DOI:10.1186/1472-6882-14-85]
29. Hashempur MH, Heydari M, Mosavat SH, Heydari ST, Shams M. Complementary and alternative medicine use in Iranian patients with Diabetes Mellitus. J Integr Med. 2015; 13(5):319-25. [DOI:10.1016/S2095-4964(15)60196-0] [DOI:10.1016/S2095-4964(15)60196-0]
30. Shiri AH, Raiatdoost E, Afkhami H, Ravanshad R, Hosseini SE, Kalani N, et al. The herbal combination of Sugarcane, Black Myrobalan, and mastic as a supplementary treatment for COVID-19: A randomized clinical trial. MedRxiv. 2021. [Link] [DOI:10.1101/2021.04.27.21256221]
31. Sadighi J, Maftoon F, Ziai SA. [Herbal medicine: Knowledge, attitude and practice in Tehran (Persian)]. J Med Plants. 2005; 4(13):60-7. [Link]
32. Hashem-Dabaghian F. [Knowledge of pregnant women about the efficacy and safety of herbal medicine and their practice during pregnancy (Persian)]. J Complement Med. 2012; 2(3):246-56. [Link]
33. Sattari M, Dilmaghanizadeh M, Hamishehkar H, Mashayekhi SO. Self-reported use and attitudes regarding herbal medicine safety during pregnancy in Iran. Jundishapur J Nat Pharm Prod. 2012; 7(2):45-9. [PMID] [DOI:10.5812/jjnpp.3416]
34. Balouchi A, Rahnama M, Hastings-Tolsma M, Shoja MM, Bolaydehyi E. Knowledge, attitude and use of complementary and integrative health strategies: A preliminary survey of Iranian nurses. J Integr Med. 2016; 14(2):121-7. [DOI:10.1016/S2095-4964(16)60245-5] [DOI:10.1016/S2095-4964(16)60245-5]
Hashem-Dabaghian F, Nojavan F, Mohammadbeigi A, Aligol M, Shokuhitabar M, Danesh A. Consumption Pattern of Black Myrobalan for Prevention and Treatment of COVID-19 and People’ Attitude Towards it in Qom, Iran: A Cross-Sectional Study. Qom Univ Med Sci J 2022; 16 (1) :52-65 URL: http://journal.muq.ac.ir/article-1-3451-en.html