Volume 16, Issue 11 (February 2023)                   Qom Univ Med Sci J 2023, 16(11): 0-0 | Back to browse issues page

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Hosseinchi M, Najafi G. Protective Effects of Hydroalcoholic Extract of Yarrow (Achillea Millefolium) on Sperm Parameters and In Vitro Fertilization (IVF) in Streptozotocin‐Induced Diabetic Male Mice. Qom Univ Med Sci J 2023; 16 (11)
URL: http://journal.muq.ac.ir/article-1-3593-en.html
1- Urmia Branch of Islamic Azad University , dvm_06@yahoo.com
2- Urmia University
Abstract:   (513 Views)
Background and objectives: The aim of this study is to evaluate the protective effect of (Achillea Millefolium) hydroalcoholic extract on sperm parameters and in vitro fertilization in mice. (Achillea Millefolium) is used as a medicinal plant with strong antioxidant and anti-inflammatory properties used to treat many diseases.
methods: In this study, 40 mice were divided into four groups include; control, Achillea Millefolium (37.5 mg per kilogram of body weight daily), Achillea Millefolium (75 mg per kilogram of body weight daily) and Achillea Millefolium (150 mg per Each kilogram of body weight daily). After the 30-day treatment period, the mice were euthanized and the parameters of total sperm count, percentage of live sperms, percentage of immature sperms, percentage of sperms with damaged DNA, and in vitro fertility were evaluated. Statistical analysis was done by one-way analysis of variances and Tukey’s post hoc test.

Results: It was found that in all three groups of Achillea Millefolium with doses (37.5, 75 and 150), an increase in the number of sperms as well as sperm viability, the percentage of fertilization was observed, and this increase had a significant difference only in the dose of 75 mg compared to the control group. But no significant difference was observed between the three groups of Achillea Millefolium.

Conclusion: The findings of this study showed that Achillea Millefolium hydroalcoholic extract can improve sperm parameters and fertility due to its antioxidant properties.

Type of Study: Original Article | Subject: بافت شناسی و جنین شناسی
Received: 2022/10/14 | Accepted: 2022/11/29 | Published: 2023/01/1

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