[Home ] [Archive]   [ فارسی ]  
:: ::
:: Volume 1, Issue 2 (6-2007) ::
2007, 1(2): 23-31 Back to browse issues page
The Trend of Antibiotic Resistance in Shigellosis and the Diagnostic Value of Erythrocyte Sedimentation Rate for Its Differentiation from Viral Gastroenteritides in Aliasghar Children Hospital, Tehran (1996-2006)
AR Nateghian *1, S Bijani2
1- Iran University of Medical Sciences , nateghian@hotmail.com
2- Iran University of Medical Sciences
Abstract:   (5578 Views)

Background and objectives
As a common infectious disease in childhood, shigellosis has a variety of seasonal and
microbiologic patterns and there is a concerning trend of resistance in various parts of the
world and even a single country. Inappropriate empiric therapy for any acute episode of
gastroenteritis, which might be based on lab studies, could potentially lead to even further
resistance. In this report, the erythrocyte sedimentation rate was studied in patients with acute
gastroenteritis.
Methods
Medical records of 117 patients were reviewed in this study. The mean and standard
deviation of some of the acute phase inflammatory indicators were compared in two groups of
shigellosis and viral gastroenteritides using independent samples t test.
Results
The mean age of the patients was 49 months, and almost half of them were male. Shigella
sonnei was the commonest species isolated from these patients. Shigellosis was found to be
more frequent during August to October. After 2001, resistance to ampicillin and
cotrimoxazole was observed in 75% and 90% of isolates respectively. A few cases were
resistant to third generation of cephalosporins (< 3%). In shigellosis, the erythrocyte
sedimentation rate was significantly higher than viral gastroenteritis.
Conclusion
Empiric use of cotrimoxazole is no longer recommended in children suspicious of
contracting shigellosis in Tehran. To avoid unnecessary prescription of antibiotics for acute
gastroenteritis, a normal result of erythrocyte sedimentation rate might be helpful.

Keywords: Gastroenteritis, Shigella, Bacterial Antibiotic Resistance, Antibiotics, Erythrocyte Sedimentation Rate
Full-Text [PDF 271 kb]   (1310 Downloads)    
Type of Study: Original Article |
Received: 2016/03/29 | Accepted: 2016/03/29 | Published: 2016/03/29
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nateghian A, Bijani S. The Trend of Antibiotic Resistance in Shigellosis and the Diagnostic Value of Erythrocyte Sedimentation Rate for Its Differentiation from Viral Gastroenteritides in Aliasghar Children Hospital, Tehran (1996-2006). Qom University of Medical Sciences Journal 2007; 1 (2) :23-31
URL: http://journal.muq.ac.ir/article-1-477-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 1, Issue 2 (6-2007) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
Persian site map - English site map - Created in 0.07 seconds with 29 queries by YEKTAWEB 4538