Qom University of Medical Sciences Journal

Background and Objectives: Adipose tissue as a source of energy, is known as an important endocrine organ that releases various hormones including resistin. Resistin plays an important role in regulation of energy homeostasis and metabolism. The effect of high-intensity interval training (HIIT) on resistin concentration in individuals is not clearly defined. The present study aimed to determine the effect of 10-weeks of HIIT on plasma resistin levels in male non-athlete students.   Methods: In this semi-experimental study, 26 male non-athlete students were randomly selected and divided into two groups of experimental and control. The experimental group performed interval trainings, in a 10-week training program (3 times a week) according to the training program with the intensity of 85-100% HRmax. Blood samples were taken after 14 hours of fasting at different stages and similar conditions, and plasma levels of resistin were measured using a resistin kit (BOSTER Company, USA). The data were analyzed using independent and dependent t-tests at the significance level of &alpha; < 0.05.   Results: In this study, 10 weeks of HIIT caused a significant decrease in the plasma levels of resistin in the experimental group compared to the control group (p&le;0.05).   Conclusion: From the obtained results, it can be said that HIIT, as a new and effective training method, has a preventive effect on cardiovascular diseases through a significant reduction of resistin.