Volume 17 -                   Qom Univ Med Sci J 2023, 17 - : 597-610 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sepehrmanesh Z, Zamani B, Pirasteh P, Rahimi H, Saei R. Prevalence of Depressive Symptoms in People With Osteoporosis Referred to the Bone Densitometry Center of a Hospital in Kashan. Qom Univ Med Sci J 2023; 17 : 2871.1
URL: http://journal.muq.ac.ir/article-1-3712-en.html
1- Department of Psychiatric, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran. , psychiatric.department@gmail.com
2- Department of Rheumatology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
3- Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
4- Department of Vital Statistics and Epidemiology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
5- Clinical Research Development Unit, Matini Hospital, Kashan University of Medical Sciences, Kashan, Iran
Abstract:   (467 Views)
Background and Objectives: Osteoporosis is a chronic disease characterized by decreased bone density and increased risk of bone fractures. Osteoporosis can affect the quality of life and lead to depression by causing bone fractures and associated complications such as reduced physical activity, weight gain, and reduced self-care. This study aims to investigate the prevalence of depression in people with osteoporosis referred to the bone densitometry center of a hospital in Kashan, Iran.
Methods: In this cross-sectional study, 150 people with osteoporosis were selected from among those referred to the bone densitometry center of Shahid Beheshti Hospital in Kashan in 2021, who were selected by a systematic sampling method. To collect information, a demographic form and Beck’s depression inventory were used. Data were analyzed in SPSS software using chi-square test and independent t-test.
Results: In this study, 86% of people with osteoporosis had depressive symptoms, of whom 42% had severe depression. The prevalence of depressive symptoms in osteoporosis patients with a T score was 37.9%, on average. There was a statistically significant difference in the severity of depression among patients in terms of the family history of depression and the use of psychiatric drugs (P<0.001).
Conclusion: The majority of people with osteoporosis in the study center in Kashan have some degree of depression symptoms, which shows the importance of early investigation and treatment of depression in these patients.
Article number: 2871.1
Full-Text [PDF 4661 kb]   (205 Downloads) |   |   Full-Text (HTML)  (159 Views)  
Type of Study: Original Article | Subject: داخلی
Received: 2023/04/10 | Accepted: 2023/06/17 | Published: 2023/08/1

References
1. Malhi GS, Mann JJ. Depression. Lancet. 2018; 392(10161):2299-312. [DOI:10.1016/S0140-6736(18)31948-2] [PMID] [DOI:10.1016/S0140-6736(18)31948-2]
2. Lee CW, Liao CH, Lin CL, Liang JA, Sung FC, Kao CH. Increased risk of osteoporosis in patients with depression: A population-based retrospective cohort study. Mayo Clin Proc. 2015; 90(1):63-70. [DOI:10.1016/j.mayocp.2014.11.009] [PMID] [DOI:10.1016/j.mayocp.2014.11.009]
3. Heim C, Binder EB. Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Exp Neurol. 2012; 233(1):102-11. [DOI:10.1016/j.expneurol.2011.10.032] [PMID] [DOI:10.1016/j.expneurol.2011.10.032]
4. World Health Organization (WHO). Depression and other common mental disorders: Global health estimates [Internet]. 2017 [Updated 2017 January 3]. Available from: [Link]
5. Rajabi GR. [Psychometric properties of Beck depression inventory short form items (BDI-13)(Persian)]. J Iran Psychol. 2005; 1(4):28-35. [Link]
6. Hemmati F, Sarokhani D, Sayehmiri K, Motadayen M. [Prevalence of osteoporosis in postmenopausal women in Iran: A systematic review and meta-analysis (Persian)]. Iran J Obstet Gynecol Infertil. 2018; 21(3):90-102. [DOI:10.22038/ijogi.2018.11068]
7. Saei Gharenaz M, Ozgoli G, Aghdashi MA, Salmany F. [Relationship between depression and osteoporosis in women (Persian)]. Urmia Med J. 2015; 26(1):10-6. [Link]
8. Oh SM, Kim HC, Ahn SV, Rhee Y, Suh I. Association between depression and bone mineral density in community-dwelling older men and women in Korea. Maturitas. 2012; 71(2):142-6. [DOI:10.1016/j.maturitas.2011.11.007] [PMID] [DOI:10.1016/j.maturitas.2011.11.007]
9. Kanis JA. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: Synopsis of a WHO report. WHO Study Group. Osteoporos Int. 1994; 4(6):368-81. [DOI:10.1007/BF01622200] [PMID] [DOI:10.1007/BF01622200]
10. Rosenblat JD, Gregory JM, Carvalho AF, McIntyre RS. Depression and disturbed bone metabolism: A narrative review of the epidemiological findings and postulated mechanisms. Curr Mol Med. 2016; 16(2):165-78. [DOI:10.2174/1566524016666160126144303] [PMID] [DOI:10.2174/1566524016666160126144303]
11. Lips P, van Schoor NM. Quality of life in patients with osteoporosis. Osteoporos Int. 2005; 16(5):447-55. [DOI:10.1007/s00198-004-1762-7] [PMID] [DOI:10.1007/s00198-004-1762-7]
12. Mezuk B, Eaton WW, Golden SH. Depression and osteoporosis: Epidemiology and potential mediating pathways. Osteoporos Int. 2008; 19(1):1-12. [DOI:10.1007/s00198-007-0449-2] [PMID] [DOI:10.1007/s00198-007-0449-2]
13. Chau K, Atkinson SA, Taylor VH. Are selective serotonin reuptake inhibitors a secondary cause of low bone density? J Osteoporos. 2012; 2012:323061 [DOI:10.1155/2012/323061] [PMID] [DOI:10.1155/2012/323061]
14. Ramasubbu R, Beaulieu S, Taylor VH, Schaffer A, McIntyre RS; Canadian Network for Mood and Anxiety Treatments (CANMAT)Task Force. The CANMAT task force recommendations for the management of patients with mood disorders and comorbid medical conditions: Diagnostic, assessment, and treatment principles. Ann Clin Psychiatry. 2012; 24(1):82-90. [PMID]
15. Ramasubbu R, Taylor VH, Samaan Z, Sockalingham S, Li M, Patten S, et al. The Canadian network for mood and anxiety treatments (CANMAT)task force recommendations for the management of patients with mood disorders and select comorbid medical conditions. Ann Clin Psychiatry. 2012; 24(1):91-109. [PMID]
16. Kallala R, Barrow J, Graham SM, Kanakaris N, Giannoudis PV. The in vitro and in vivo effects of nicotine on bone, bone cells and fracture repair. Expert Opin Drug Saf. 2013; 12(2):209-33. [DOI:10.1517/14740338.2013.770471] [PMID] [DOI:10.1517/14740338.2013.770471]
17. Kaidanovich-Beilin O, Cha DS, McIntyre RS. Crosstalk between metabolic and neuropsychiatric disorders. F1000 Biol Rep. 2012; 4:14. [DOI:10.3410/B4-14] [PMID] [PMCID] [DOI:10.3410/B4-14]
18. Graff LA, Walker JR, Bernstein CN. Depression and anxiety in inflammatory bowel disease: A review of comorbidity and management. Inflamm Bowel Dis. 2009; 15(7):1105-18. [DOI:10.1002/ibd.20873] [PMID] [DOI:10.1002/ibd.20873]
19. Carter MI, Hinton PS. Physical activity and bone health. Mo Med. 2014; 111(1):59-64. [PMID] [PMCID]
20. DiVasta AD, Gordon CM. Exercise and bone: Where do we stand? Metabolism. 2013; 62(12):1714-7. [DOI:10.1016/j.metabol.2013.09.016] [PMID] [DOI:10.1016/j.metabol.2013.09.016]
21. Mead GE, Morley W, Campbell P, Greig CA, McMurdo M, Lawlor DA. Exercise for depression. Cochrane Database Syst Rev. 2008; (4):CD004366. [DOI:10.1002/14651858.CD004366.pub3] [PMID] [DOI:10.1002/14651858.CD004366.pub3]
22. Hsiao MC, Liu CY, Wang CJ. Factors associated with low bone density among women with major depressive disorder. Int J Psychiatry Med. 2012; 44(1):77-90. [DOI:10.2190/PM.44.1.f] [PMID] [DOI:10.2190/PM.44.1.f]
23. Drosselmeyer J, Rapp MA, Hadji P, Kostev K. Depression risk in female patients with osteoporosis in primary care practices in Germany. Osteoporos Int. 2016; 27(9):2739-44. [DOI:10.1007/s00198-016-3584-9] [PMID] [DOI:10.1007/s00198-016-3584-9]
24. Zabihi Yeganeh M, Jahed S, Rajaei A, Amini H. [The relationship between major depression and bone density (Persian)]. Res Med. 2008; 32(4):267-70. [Link]
25. Derakhshan S, Salehi R, Reshadmanesh N. [Prevalence of osteoporosis, osteopenia and their related factors in post-menopausal women referring to Kurdistan densitometry center (Persian)]. Sci J Kurdistan Univ Med Sci. 2006; 11(2):59-67. [Link]
26. Safari R, Aghaei M, ShadpourRashti H, Bazrafshan H, Qorbani M. [Prevalence of osteoporosis and its association with demographic characterirstics-Gorgan, Iran (Persian)]. Hormozgan Med J. 2011; 15(1):56-62. [Link]
27. Jamshidian-Tehrani M, Kalantari N, Azadbakht L, Esmaillzadeh A, Rajaie A, Houshiar-rad A, et al. [Osteoporosis risk factors in Tehrani women aged 40-60 years (Persian)]. Iran J Endocrinol Metab. 2004; 6(2):139-45. [Link]
28. Michelson D, Stratakis C, Hill L, Reynolds J, Galliven E, Chrousos G, et al. Bone mineral density in women with depression. N Engl J Med. 1996; 335(16):1176-81. [DOI:10.1056/NEJM199610173351602] [PMID] [DOI:10.1056/NEJM199610173351602]
29. World Health Organization (WHO). WHO scientific group on the assessment of osteoporosis at primary health care level. Geneva: World Health Organization; 2004. [Link]
30. Govender C, Du Plessis AM, Bipath P, Povey D, Viviers G, Viljoen M. Bone density and depression in premenopausal South African women: A pilot study. Afr J Psychiatry. 2010; 13(1):58-60. [DOI:10.4314/ajpsy.v13i1.53431] [PMID] [DOI:10.4314/ajpsy.v13i1.53431]
31. Cizza G, Ravn P, Chrousos GP, Gold PW. Depression: A major, unrecognized risk factor for osteoporosis? Trends Endocrinol Metab. 2001; 12(5):198-203. [DOI:10.1016/S1043-2760(01)00407-6] [PMID] [DOI:10.1016/S1043-2760(01)00407-6]
32. Reginster JY, Deroisy R, Paul I, Hansenne M, Ansseau M. Depressive vulnerability is not an independent risk factor for osteoporosis in postmenopausal women. Maturitas. 1999; 33(2):133-7. [DOI:10.1016/S0378-5122(99)00057-2] [PMID] [DOI:10.1016/S0378-5122(99)00057-2]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Qom University of Medical Sciences Journal

Designed & Developed by : Yektaweb