Research code: 14001409
Ethics code: 1400.137
Clinical trials code: 1788
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Bahadori A, Eshagh Hossaini S K, Hamta A, Khaksar M R, Moradi Dehnavi H, Salimi Amroud M. The Five-year Survival Rate of Children With Acute Myeloid and Acute Lymphocytic Leukemia Referred to a Hospital in Qom, Iran and the Related Factors. Qom Univ Med Sci J 2024; 18 : 823.5
URL: http://journal.muq.ac.ir/article-1-3834-en.html
URL: http://journal.muq.ac.ir/article-1-3834-en.html
Arezoo Bahadori * 
1, Seyed Kamal Eshagh Hossaini2 , Amir Hamta3 , Mohammad Reza Khaksar4 , Hossein Moradi Dehnavi5 , Mohammad Salimi Amroud6
1, Seyed Kamal Eshagh Hossaini2 , Amir Hamta3 , Mohammad Reza Khaksar4 , Hossein Moradi Dehnavi5 , Mohammad Salimi Amroud6
1- Clinical Research Development Center, Pediatric Center of Hazrat Masoumeh, Qom University of Medical Science, Qom, Iran. , bahadori5891@gmail.com
2- Department of Pediatrics, Faculty of Medicine, Hazrat-e Fateme Masoume Hospital, Qom University of Medical Sciences, Qom, Iran.
3- Department of Biostatistics, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
4- Department of Occupational Health, Research Center for Environmental Pollutants, Faculty of Health, Qom University of Medical Sciences, Qom, Iran.
5- Department of Persian Medicine, Faculty of Traditional Medicine, Spiritual Health Research Center, Qom University of Medical Sciences, Qom, Iran.
6- International Patient Department, Qom University of Medical Science, Qom, Iran.
2- Department of Pediatrics, Faculty of Medicine, Hazrat-e Fateme Masoume Hospital, Qom University of Medical Sciences, Qom, Iran.
3- Department of Biostatistics, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
4- Department of Occupational Health, Research Center for Environmental Pollutants, Faculty of Health, Qom University of Medical Sciences, Qom, Iran.
5- Department of Persian Medicine, Faculty of Traditional Medicine, Spiritual Health Research Center, Qom University of Medical Sciences, Qom, Iran.
6- International Patient Department, Qom University of Medical Science, Qom, Iran.
Abstract: (341 Views)
Background and Objectives: Leukemia is the most common childhood cancer. The incidence and survival rates for leukemia in different regions are different due to various environmental, race-genetic, cultural, social, and economic conditions. This study aimed to determine the five-year survival rate of children with acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL) in Qom Province, Iran and find the effective factors.
Methods: This is a retrospective cohort study on 196 children with AML or ALL admitted to the oncology department of Hazrat-e Masoumeh Hospital in Qom, Iran, during 2017-2023. Data were collected from the medical files of children and using a questionnaire completed through a telephone interview with parents. Data analysis was done using the Kaplan-Meier method and log-rank test, and data modeling was done using the Cox regression model in STATA software, version 21.
Results: Most of the children had blood group O (n=62, 31.6%) and Rhesus (Rh) positive (n=154, 78.6%). The five-year survival rate was significantly different in terms of blood group and Rh factor (P<0.05). The chance of survival in the ALL group (102±59.4 months) was higher than in the AML group (81.5±44.2 months).
Conclusion: The five-year survival rate in children with ALL in Qom Province is higher than in children with AML. Blood group and Rh factors affected the survival rate.
Methods: This is a retrospective cohort study on 196 children with AML or ALL admitted to the oncology department of Hazrat-e Masoumeh Hospital in Qom, Iran, during 2017-2023. Data were collected from the medical files of children and using a questionnaire completed through a telephone interview with parents. Data analysis was done using the Kaplan-Meier method and log-rank test, and data modeling was done using the Cox regression model in STATA software, version 21.
Results: Most of the children had blood group O (n=62, 31.6%) and Rhesus (Rh) positive (n=154, 78.6%). The five-year survival rate was significantly different in terms of blood group and Rh factor (P<0.05). The chance of survival in the ALL group (102±59.4 months) was higher than in the AML group (81.5±44.2 months).
Conclusion: The five-year survival rate in children with ALL in Qom Province is higher than in children with AML. Blood group and Rh factors affected the survival rate.
Article number: 823.5
Type of Study: Original Article |
Subject:
کودکان
Received: 2023/10/15 | Accepted: 2024/06/26 | Published: 2024/04/29
Received: 2023/10/15 | Accepted: 2024/06/26 | Published: 2024/04/29
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