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Makarian Poor F, Esna-Ashari F, Borzouei S. Relationship Between Beliefs About Medications and Adherence to Treatment in Iranian Patients With Dyslipidemia. Qom Univ Med Sci J 2025; 19 (1) : 3107.1
URL: http://journal.muq.ac.ir/article-1-3998-en.html
1- Department of Internal Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
2- Department of Social Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
3- Department of Endocrinology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. , borzooeishiva@yahoo.com
Abstract:   (475 Views)
Background and Objectives: Dyslipidemia has significant risks for health. The importance of medication adherence in managing and preventing dyslipidemia complications has been emphasized. Patient beliefs about medications may influence their adherence to treatment. Therefore, this study aimed to investigate the relationship between the patient beliefs about medications and adherence to treatment in Iranian patients with dyslipidemia.
Methods: This analytical cross-sectional study was conducted in 2022-2023 on 243 patients with dyslipidemia referred to a specialized endocrinology clinic in Hamadan, Iran. They completed a demographic/clinical checklist, the 8-item Morisky medication adherence scale (MMAS-8), and the beliefs about medicines questionnaire (BMQ). Data were analyzed using the chi-square test and Spearman’s correlation test in SPSS software, version 26. The significance level was set at 0.05. 
Results: There was a positive and significant correlation between the MMAS-8 score and the BMQ score in total (P<0.001) and in the subscales of general-overuse (P<0.001), general-harm (P<0.001), and specific-concerns (P=0.016).
Conclusion: Patients with dyslipidemia who have positive beliefs about medications are more likely to take their medications as prescribed. Therefore, healthcare professionals should assess patients’ beliefs about their medicines and provide them with detailed information. This may increase patients’ motivation and confidence in managing their lipid disorders with medications.
Article number: 3107.1
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Type of Study: Original Article | Subject: غدد
Received: 2024/08/10 | Accepted: 2024/12/7 | Published: 2025/03/30

References
1. Biniaz V, Sadeghi Shermeh M, Tayebi A, Ebadi A, Nemati E. [Background and Objectives: Dyslipidemia is a common disorder and one of the major causes of the atherosclerosis development and progression in hemodialysis patients. Timely diagnosis and treatment of dyslipidemia can reduce mortality and morbidity of cardi (Persian)]. Qom Univ Med Sci J. 2014; 8(1):10-5. [Link]
2. Vajdi M, Karimi A, Farhangi MA, Ardekani AM. The association between healthy lifestyle score and risk of metabolic syndrome in Iranian adults: A cross-sectional study. BMC Endocr Disord. 2023; 23(1):16. [DOI:10.1186/s12902-023-01270-0] [PMID] [PMCID] [DOI:10.1186/s12902-023-01270-0]
3. Maleki Jamasbi M, Azami H, Samari B, Yousofvand V, Shourcheh E. [Epidemiological survey of mortality and morbidity caused by cardiovascular diseases in patients admitted to the cardiac care units of Hamadan Educational-medical Hospitals, Hamadan, Iran, in 2017 (Persian)]. J Health Res Commun. 2019; 5(3):27-38. [Link]
4. Thongtang N, Sukmawan R, Llanes EJB, Lee ZV. Dyslipidemia management for primary prevention of cardiovascular events: Best in-clinic practices. Prev Med Rep. 2022; 27:101819.[DOI:10.1016/j.pmedr.2022.101819] [PMID] [PMCID] [DOI:10.1016/j.pmedr.2022.101819]
5. Alefishat E, Jarab AS, Al-Qerem W, Abu-Zaytoun L. Factors associated with medication non-adherence in patients with dyslipidemia. Healthcare (Basel). 2021; 9(7):813. [DOI:10.3390/healthcare9070813] [PMID] [PMCID] [DOI:10.3390/healthcare9070813]
6. Esna-Ashari F, Heidari M, Faiba F, Pirdehghan A, Sangestani M. [Examining beliefs about medicines and drug regimen adherence among hypertensive patients in Hamadan City, Iran (Persian)]. Qom Univ Med Sci J. 2023; 17:E2860.1. [Link]
7. Baghcheghi N, Koohestani HR. [Beliefs about medicines and its relationship with medication adherence in patients with chronic diseases (Persian)]. Qom Univ Med Sci J. 2021; 15(6):444-53. [DOI:10.32598/qums.15.6.2414.1] [DOI:10.32598/qums.15.6.2414.1]
8. Desai NR, Farbaniec M, Karalis DG. Nonadherence to lipid-lowering therapy and strategies to improve adherence in patients with atherosclerotic cardiovascular disease. Clin Cardiol. 2023; 46(1):13-21. [DOI:10.1002/clc.23935] [PMID] [PMCID] [DOI:10.1002/clc.23935]
9. Piña IL, Di Palo KE, Brown MT, Choudhry NK, Cvengros J, Whalen D, et al. Medication adherence: Importance, issues and policy: A policy statement from the American Heart Association. Prog Cardiovasc Dis. 2021; 64:111-20. [DOI:10.1016/j.pcad.2020.08.003] [PMID] [DOI:10.1016/j.pcad.2020.08.003]
10. van Driel ML, Morledge MD, Ulep R, Shaffer JP, Davies P, Deichmann R. Interventions to improve adherence to lipid-lowering medication. Cochrane Database Syst Rev. 2016; 12(12):CD004371. [DOI:10.1002/14651858.CD004371] [DOI:10.1002/14651858.CD004371]
11. Jiang S, Luo T, Zhu Z, Huang Y, Liu H, Li B, et al. Latent profile analysis of medication beliefs in patients with type 2 Diabetes in the hospital-home transition and comparison with medication adherence. Patient Preference and Adherence. 2024; 18:839-53. [DOI:10.2147/PPA.S450107] [PMID] [DOI:10.2147/PPA.S450107]
12. Baryakova TH, Pogostin BH, Langer R, McHugh KJ. Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems. Nat Rev Drug Discov. 2023; 22(5):387-409. [DOI:10.1038/s41573-023-00670-0] [PMID] [PMCID] [DOI:10.1038/s41573-023-00670-0]
13. Mathew MR. Factors associated with medication adherence among Dyslipidemic patients in Kottayam district, Kerala, India [MA thesis]. Kerala: SCTIMST; 2013. [Link]
14. Moharamzad Y, Saadat H, Nakhjavan Shahraki B, Rai A, Saadat Z, Aerab-Sheibani H, et al. Validation of the Persian version of the 8-item Morisky Medication Adherence Scale (MMAS-8) in Iranian hypertensive patients. Glob J Health Sci. 2015; 7(4):173-83. [DOI:10.5539/gjhs.v7n4p173] [PMID] [PMCID] [DOI:10.5539/gjhs.v7n4p173]
15. Menckeberg TT, Bouvy ML, Bracke M, Kaptein AA, Leufkens HG, Raaijmakers JA, et al. Beliefs about medicines predict refill adherence to inhaled corticosteroids. J Psychosom Res. 2008; 64(1):47-54. [DOI:10.1016/j.jpsychores.2007.07.016] [PMID] [DOI:10.1016/j.jpsychores.2007.07.016]
16. Minaiyan M, Taheri M, Mirmoghtadaee P, Maracy MR. [Comparative role of demographic factors and patient's belief about pre-scribed medicine on adherence to drug treatment in chronic diseases (Persian)]. J Isfahan med sch. 2011; 29(156):1469-77. [Link]
17. Sipos M, Farcas A, Prodan N, Mogosan C. Relationship between beliefs about medicines and adherence in elderly patients with cardiovascular and respiratory diseases: A cross-sectional study in Romania. Patient Educ Couns. 2021; 104(4):911-8. [DOI:10.1016/j.pec.2020.09.001] [PMID] [DOI:10.1016/j.pec.2020.09.001]
18. Horne R, Albert A, Boone C. Relationship between beliefs about medicines, adherence to treatment, and disease activity in patients with rheumatoid arthritis under subcutaneous anti-TNFα therapy. Patient Prefer Adherence. 2018; 12:1099-111. [DOI:10.2147/PPA.S166451] [PMID] [PMCID] [DOI:10.2147/PPA.S166451]
19. Wu P, Liu N. Association between patients' beliefs and oral antidiabetic medication adherence in a Chinese type 2 diabetic population. Patient Prefer Adherence. 2016; 10:1161-7. [DOI:10.2147/PPA.S120446] [PMID] [PMCID] [DOI:10.2147/PPA.S120446]
20. Al-Tarawneh F, Ali T, Al-Tarawneh A, Altwalbeh D, Gogazeh E, Bdair O, Algaralleh A. Study of adherence level and the relationship between treatment adherence, and superstitious thinking related to health issues among chronic disease patients in southern Jordan: cross-sectional study. Patient Prefer Adherence. 2023; 17:605-14. [DOI:10.2147/PPA.S390997] [PMID] [PMCID] [DOI:10.2147/PPA.S390997]
21. de Vries ST, Keers JC, Visser R, de Zeeuw D, Haaijer-Ruskamp FM, Voorham J, et al. Medication beliefs, treatment complexity, and non-adherence to different drug classes in patients with type 2 diabetes. J Psychosom Res. 2014; 76(2):134-8. [DOI:10.1016/j.jpsychores.2013.11.003] [PMID] [DOI:10.1016/j.jpsychores.2013.11.003]
22. Horne R, Chapman SC, Parham R, Freemantle N, Forbes A, Cooper V. Understanding patients' adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the Necessity-Concerns Framework. PLoS One. 2013; 8(12):e80633. [DOI:10.1371/journal.pone.0080633] [PMID] [PMCID] [DOI:10.1371/journal.pone.0080633]
23. Shahin W, Kennedy GA, Stupans I. The impact of personal and cultural beliefs on medication adherence of patients with chronic illnesses: a systematic review. Patient Prefer Adherence. 2019; 13:1019-35. [DOI:10.2147/PPA.S212046] [PMID] [PMCID] [DOI:10.2147/PPA.S212046]
24. Sheils E, Tillett W, James D, Brown S, Dack C, Family H, et al. Changing medication-related beliefs: A systematic review and meta-analysis of randomized controlled trials. Health Psychol. 2024; 43(3):155-70. [DOI:10.1037/hea0001316] [PMID] [DOI:10.1037/hea0001316]
25. Sawhney JP, Ramakrishnan S, Madan K, Ray S, Jayagopal PB, Prabhakaran D, et al. CSI clinical practice guidelines for dyslipidemia management: Executive summary. Indian Heart J. 2024; 76(S 1):S6-19. [DOI:10.1016/j.ihj.2023.11.271] [PMID] [PMCID] [DOI:10.1016/j.ihj.2023.11.271]
26. Yao S, Lix LM, Teare G, Evans C, Blackburn DF. Physician influence on medication adherence, evidence from a population-based cohort. PLoS One. 2022; 17(12):e0278470. [DOI:10.1371/journal.pone.0278470] [PMID] [PMCID] [DOI:10.1371/journal.pone.0278470]
27. Kasahun AE, Sendekie AK, Mekonnen GA, Sema FD, Kemal LK, Abebe RB. Impact of personal, cultural and religious beliefs on medication adherence among patients with chronic diseases at University Hospital in Northwest Ethiopia. Patient Prefer Adherence. 2022; 16:1787-803. [DOI:10.2147/PPA.S370178] [PMID] [PMCID] [DOI:10.2147/PPA.S370178]
28. Foley L, Larkin J, Lombard-Vance R, Murphy AW, Hynes L, Galvin E, et al. Prevalence and predictors of medication non-adherence among people living with multimorbidity: a systematic review and meta-analysis. BMJ Open. 2021; 11(9):e044987. [DOI:10.1136/bmjopen-2020-044987corr1] [PMID] [PMCID] [DOI:10.1136/bmjopen-2020-044987corr1]
29. Oates GR, Juarez LD, Hansen B, Kiefe CI, Shikany JM. Social risk factors for medication nonadherence: findings from the CARDIA study. Am J Health Behav. 2020; 44(2):232-43. [DOI:10.5993/AJHB.44.2.10] [PMID] [PMCID] [DOI:10.5993/AJHB.44.2.10]

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