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Qom Univ Med Sci J 2014, 7(6): 27-33 Back to browse issues page
Effect of Probiotic Supplement on Immune Response in Male Athletes:
Marzieh Aghaee1, Nikoo Khosravi2, Parichehr Hanachi2, Mohammad Reza Kordi3, Rohollah Aghaee4
1- Qom University of Medical Sciences , marzieh.aghaei@yahoo.com
2- Alzahra University
3- University of Tehran
4- Office of Education District 4, Qom
Abstract:   (6506 Views)

Background and Objectives: Probiotics are live microorganisms, which if administered in adequate amounts,have beneficial effects on host health. Probioticsreduces the risk of developing diseases in the consumers through prevention of the immunosuppressive effects. The present study was performed with the purpose of comparing the effect of probiotic supplementation on the immune response in male athletes, before and after exhaustive exercise.   Methods: In a double-blind study, 16 male athlete volunteers aged between 19-25 years were assigned into two groups of experimental and placebo. Subjects of the experimental and placebo respectively tooktwo capsules of probiotic or placebo daily for 30 days. Blood samples of the participants were collected at the beginning and on the 30th day, and the numbers of lymphocytes, monocytes, granulocytes, serum CRP, and serum IgA were measured. Data were analyzed using repeated measurement method and independent t-test.   Results: Consumption of probiotics supplement in the rest levels in the intragroup and intergroup comparison,only showed significant difference (p<0.05) in the monocytes levels compared to base line level.Also, after the exhaustive exercise, a statistically significant difference was observed in the levels of monocytes, granulocytes, and lymphocytes compared to the baseline levels.In the comparison between the probiotic and placebo groups,only the monocytes level were significantly different (p<0.05). Other variables had nosignificant differences.   Conclusion: The results of this study showed that probiotic consumption following exhaustive exercise can cause increase infactors of lymphocyte, monocyte, and geranolocyte, thereforeit seems that probiotics play a role in the development of immune system.  

Keywords: CRP, Immunoglobulin A, Males, Athletes, Exhaustive Exercise, Probiotic, Immune System, A Randomized Clinical Trail.
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Type of Study: Original Article |
Received: 2016/02/13 | Accepted: 2016/02/23 | Published: 2016/02/23
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Aghaee M, Khosravi N, Hanachi P, Kordi M R, Aghaee R. Effect of Probiotic Supplement on Immune Response in Male Athletes:. Qom Univ Med Sci J 2014; 7 (6) :27-33
URL: http://journal.muq.ac.ir/article-1-163-en.html

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Volume 7, Issue 6 (1-2014) Back to browse issues page
مجله دانشگاه علوم پزشکی قم Qom University of Medical Sciences Journal
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