Volume 15, Issue 4 (July 2021)                   Qom Univ Med Sci J 2021, 15(4): 306-311 | Back to browse issues page

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Alipour M, Khashei Varnamkhasti K, Eslami Moghaddam M. A Case Report of Neonatal Pemphigus Vulgaris. Qom Univ Med Sci J 2021; 15 (4) :306-311
URL: http://journal.muq.ac.ir/article-1-3125-en.html
A Case Report of Neonatal Pemphigus Vulgaris
Marzieh Alipour1 , Khalil Khashei Varnamkhasti * 2, Marzieh Eslami Moghaddam3
1- Department of Genetics, School of Medicine, Kazerun Branch, University of Islamic Azad, Iran.
2- Department of Genetics, School of Medicine, Kazerun Branch, University of Islamic Azad, Iran. , khalil.khashei2016@gmail.com
3- Obstetrics and Gynecology Ward, Kazerun Hospital Valiasr, Kazerun, Iran.
Abstract:   (1872 Views)
Background and Objectives: Pemphigus vulgaris (PV) is a chronic, rare mucocutaneous autoimmune bullous disease characterized by flaccid blisters and or pustules, with secondary erosions of the mucous membranes or skin. PV threatens the patient life by forming splits within the epidermis, accompanied by acantholysis (separating keratinocytes from each other).
Case Presentation: Our case is a term female neonate with PV, born of a 31-year-old mother. On initial examination by a pediatrician, several thin-walled flaccid blisters and burst blisters accompanied with open sores were observed on the skin of hands, feet, face, and mucosa of the oral cavity, tongue, and throat. A positive Nikolsky's sign confirmed her involvement with the disease.
Keywords: Pemphigus vulgaris, Pemphigus, Autoimmune, Mucocutaneous
Full-Text [PDF 1656 kb]   (617 Downloads)    
Type of Study: CASE STUDY | Subject: پوست و مو
Received: 2021/05/2 | Accepted: 2021/05/26 | Published: 2021/07/1
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