Qom University of Medical Sciences Journal

Background and Objectives: Celiac disease can be associated with various extra intestinal symptoms such as primary biliary cirrhosis and auto immune hepatitis but idiopathic portal hypertension is a very rare phenamenon. IPH patient typically has splenomegally, esophageal varices and sometimes Icter and ascitis.

Case Report: A case of IPH in a 38 year old woman with celiac disease. She had been suffering from Ascites, Splenomegally, malaise and apathy for several years and had undergone treatment for cryptogenic cirrhosis. Diagnostic re-examination of the patient such as Serology tests and markers from Wilson disease, auto immune and viral hepatitis showed negative reports, but her liver function test and ESR were prolonged In upper GI endoscopy esophageal varices was detected. Abdominal sonography reported moderate to severe splenomegally and rise of portal vein diameter but did not show any evidence of thrombosis. Liver biopsy revealed no sign of cirrhosis. But duodenal biopsy and serologic finding were compatible with celiac disease. Her symptoms improved on a gluten-free diet and her liver function test and ESR were normal.