Qom University of Medical Sciences Journal

Background and Objectives: Vaspin is a molecule belonging to the adipokine family. hs-CRP is the most sensitive predictive inflammatory marker for cardiovascular diseases. The aim of the present research was to determine the effect of 8 weeks of resistance training on the plasma level of vaspin, hs-CRP, and some anthropometric variables in overweight and obese young women.

Methods: In this quasi-experimental study with pre-test and post-test design, 22 inactive students with body mass index (BMI)>25Kg/m² were purposefully selected and randomly divided into two groups: 1) Resistance training group (N=12); 2) Control of (N=10). Blood samples were taken before and after the training, after 12 hours of overnight fasting, 24 hours before the start of training, and 48 hours after the last training session. The experimental group performed an 8-week training in 8 stations, with 65-80% of one repetition maximum, 4 sessions of 45 min per week. Data were analyzed by Kolmogorov-Smirnov, dependent t-, and independent t-tests (for comparison between the groups). The significance level was considered to be α< 0.05.

Results: In the experimental group, 8 weeks of resistance training in the in intragroup comparison, significant changes was observed in Vaspin, hs-CRP, and all anthropometric indicators (p<0.05). Also, in the intergroup changes, a significant change was observed in VO₂max level (p<0.05).

Conclusion: The results of this study showed that 8 weeks of resistance training can reduce the risk of cardiovascular disease in overweight and obese girles thorough decrease in vaspin and hs-CRP.